Blood Bank Clinical Tools
Professional-grade tools for antibody identification, blood unit compatibility, and transfusion reaction management—featuring Fisher's exact test analysis, population-based compatibility calculations, and evidence-based clinical protocols.
Compatibility Calculator
Calculate RBC compatibility percentages based on patient phenotype and antibody profile using population antigen frequencies.
- Patient phenotype input
- Antibody-based unit matching
- Population frequency calculations
- Extended antigen matching
Reactions
Evidence-based transfusion reaction classification, management protocols, and quick reference for clinical decision support.
- Symptom-based reaction classifier
- GRADE evidence ratings
- Management protocols
- TRALI vs TACO differentiation
Consent Risk Calculator
Evidence-based risk estimates for adverse transfusion events to support informed consent discussions with patients.
- Risks by product type (RBC, PLT, FFP, Cryo)
- Cumulative risk calculations
- Infectious disease transmission risks
- Ready-to-use consent language templates
Testing Risk Stratification
Quantify hemolytic transfusion reaction risk based on pre-transfusion compatibility testing status for clinical decision support.
- HTR risk by testing scenario
- Special population risk modifiers
- Urgency-based recommendations
- Documentation templates
Test Panel
Mark positive and negative reactions on panel cells and calculate p-values using Fisher's exact test for statistical antibody identification.
- Server-side pagination for large datasets
- Real-time p-value calculations
- Automatic exclusion tracking
- Persist selections across pages
Panel Builder
Build custom selected cell panels, search by phenotype, auto-generate optimal panels, and track antigen exclusions in real-time.
- Phenotype-based cell search
- Auto-build optimal panels
- Visual exclusion tracking grid
- Save and load work-up sessions
Antibody Identification Workflow
- Identify non-reactive rows to establish exclusions based on negative reactions.
- Cross off antigens that are homozygously expressed on non-reactive cells (double-dose cells provide stronger exclusion).
- Review positive reactions and look for a pattern using the "rule of three" for statistical confidence.
- Determine if additional cells are needed to complete the workup with sufficient coverage.
- Check the autocontrol to distinguish allo-antibodies from auto-antibodies.
- Perform additional tests (enzyme panels, select cells) to confirm antibody specificity.
- Report conclusions including clinical significance and transfusion recommendations.
Key Features
Phenotype Search
Find cells by antigen profile (e.g., Fy(a+b-), K+, homozygous cells)
Auto-Build Panels
Automatically create optimal panels with homozygous cell coverage
Exclusion Tracking
Visual display of ruled-out antigens with single and double-dose indicators
Save Work-ups
Save and load antibody identification sessions for later review
Export & Print
Generate printable worksheets in HTML or export data as CSV
Statistical Analysis
Fisher's exact test with p-value calculations for confident identification
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